Hydrochloric Acid → 1,3-dihydro-1-(2-dimethylaminoethyl)-4,5,6-tribromo-2H-benzimidazol-2-one hydrochloride

HRID 373054Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 373054
[CH3:1][N:2]([CH3:18])[CH2:3][CH2:4][N:5]1[C:9]2[CH:10]=[C:11]([Br:16])[C:12]([Br:15])=[C:13]([Br:14])[C:8]=2[NH:7][C:6]1=[O:17].C(OCC)(=O)C.[ClH:25]>C(O)C.O1CCOCC1>[ClH:25].[CH3:1][N:2]([CH3:18])[CH2:3][CH2:4][N:5]1[C:9]2[CH:10]=[C:11]([Br:16])[C:12]([Br:15])=[C:13]([Br:14])[C:8]=2[NH:7][C:6]1=[O:17]

Komponenten

6

Edukt 3

HCID 313Hydrochloric AcidHCID 8857Ethyl AcetateHCID 198113371,3-dihydro-1-(2-dimethylaminoethyl)-4,5,6-tribromo-2H-benzimidazol-2-one

Produkt 1

HCID 198113361,3-dihydro-1-(2-dimethylaminoethyl)-4,5,6-tribromo-2H-benzimidazol-2-one hydrochloride

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 702EthanolLösungsmittelHCID 312751,4-DioxaneLösungsmittel

Versuchsvorschrift

To a solution of 1,3-dihydro-1-(2-dimethylaminoethyl)-4,5,6-tribromo-2H-benzimidazol-2-one (270 mg) in ethanol (5 ml)/ethyl acetate (40 ml) was added 4N hydrogen chloride in dioxane dropwise with stirring. The separated crystals were collected by suction and dried to give 260 mg of 1,3-dihydro-1-(2-dimethylaminoethyl)-4,5,6-tribromo-2H-benzimidazol-2-one hydrochloride.

Aufarbeitung

  1. customThe separated crystals were collected by suction
  2. customdried

Quellen und Nachweise

ORD-Eintrag
ord-67edb407a89c466ebd2195ecf2df9494
Quelldatensatz
uspto-grants-1992_11
Patentnummer
US05162318

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