Ammonia → HCID 131717620, compound

HRID 373108Notes

Reaction equation

HRID 373108 reaction equation
[CH3:1][N:2]1[C:9](=[O:10])[CH:8]([C:11](=[O:37])[NH:12][C:13]2[CH:18]=[C:17]([Cl:19])[C:16]([O:20][C:21]([F:35])([F:34])[CH:22]([O:24][C:25]([F:33])([F:32])[C:26]([F:31])([F:30])[CH:27]([F:29])[F:28])[F:23])=[C:15]([Cl:36])[CH:14]=2)[C:6](=[O:7])[N:5]([CH3:38])[C:3]1=[O:4].N>C(#N)C>[NH4+:2].[CH3:38][N:5]1[C:6](=[O:7])[CH:8]([C:11](=[O:37])[NH:12][C:13]2[CH:18]=[C:17]([Cl:19])[C:16]([O:20][C:21]([F:35])([F:34])[CH:22]([O:24][C:25]([F:32])([F:33])[C:26]([F:30])([F:31])[CH:27]([F:29])[F:28])[F:23])=[C:15]([Cl:36])[CH:14]=2)[C:9](=[O:10])[N:2]([CH3:1])[C:3]1=[O:4]

Participants

4

Reactant 2

HCID 222AmmoniaHCID 88506377HCID 88506377, compound

Product 1

HCID 131717620HCID 131717620, compound

Reagents, catalysts & solvents 1

HCID 6342AcetonitrileSolvent

Conditions

Temperature
50 °C

Procedure

5.0 g (8.2 mmol) of 1,3-dimethyl-5-(3,5-dichloro-(4-(2-(1,1,2,2,3,3-hexafluoropropoxy)-1,1,2-trifluoroethoxy))phenylcarbamoyl)-barbituric acid were suspended in 50 ml of absolute acetonitrile. Ammonia was passed in at room temperature for 10 minutes and the mixture was stirred at 50° C. for 10 minutes. The precipitate which had separated out was filtered off with suction, washed with ether and dried.

Workup

  1. customThe precipitate which had separated out
  2. filtrationwas filtered off with suction
  3. washwashed with ether
  4. customdried

Sources & evidence

ORD record
ord-b3556b814baa4493901324c834db58e4
Source dataset
uspto-grants-1992_11
Patent number
US05162327

Reaction notes

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