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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 373146Generated: October 25, 2026

Pyridine, 3-(2-chloroethyl)-, hydrochloride → 1-[2-(3,4-Dimethoxyphenyl)ethyl]-4-(4-methylsulfonylaminophenylthio)piperidine

https://huagongshe.com/reaction/373146

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPyridine, 3-(2-chloroethyl)-, hydrochlorideHCID 199465—
Reactant4-(2-Chloroethyl)-1,2-dimethoxybenzeneHCID 3015359—
Reactant4-(4-Methylsulfonylaminophenylthio)-1-[2-(3-pyridyl)ethyl]piperidineHCID 15615421—
Product1-[2-(3,4-Dimethoxyphenyl)ethyl]-4-(4-methylsulfonylaminophenylthio)piperidineHCID 15615422—

Reaction Steps

The same procedure as that of Example 1 (1) to (8) was repeated except that 2-(3-pyridyl)ethyl chloride hydrochloride was replaced with 3,4-dimethoxyphenethyl chloride to prepare the intended compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05162347
Source datasetuspto-grants-1992_11
ORD IDord-49220890dab244dc80857fcfbe992d4a
Source noteuspto-grants-1992_11