HCID 19812014, compound → 3-Amino-5-dihexylaminomethylisoxazole

HRID 373172Notes

Reaction equation

HRID 373172 reaction equation
C(N(CCCC)CC#CC#N)CCC.[CH2:15]([N:21]([CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH3:32])[CH2:22][C:23]#[C:24][C:25]#[N:26])[CH2:16][CH2:17][CH2:18][CH2:19][CH3:20].C(#N)C#CCCCCCCCCCCCC.NC1C=C(CN(CCCC)CCCC)[O:52][N:51]=1>>[NH2:26][C:25]1[CH:24]=[C:23]([CH2:22][N:21]([CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH3:20])[CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH3:32])[O:52][N:51]=1

Participants

5

Reactant 4

HCID 19812014HCID 19812014, compoundHCID 19812027HCID 19812027, compoundHCID 198120394-Dibutylamino-2-butynenitrileHCID 542768904-Dihexylaminobutynenitrile

Product 1

HCID 198120323-Amino-5-dihexylaminomethylisoxazole

Procedure

When in the procedure of Example 9(a) an appropriate amount of 4-dibutylamino-2-butynenitrile or 4-dihexylaminobutynenitrile was substituted for 2-pentadecynenitrile, 3-amino-5-dibutylaminomethylisoxazole, and 3-amino-5-dihexylaminomethylisoxazole were obtained respectively, and when each of these isoxazoles was substituted for 3-amino-5-dodecylisoxazole in the procedure of Example 9(b), the following compounds were obtained:

Sources & evidence

ORD record
ord-1ed7993998be43269c7bdf52a15928dc
Source dataset
uspto-grants-1992_11
Patent number
US05162360

Reaction notes

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