Potassium Hydroxide → HCID 131717627, compound

HRID 373204Notes

Reaction equation

HRID 373204 reaction equation
[F:1][C:2]([F:32])([F:31])[C:3]1[CH:4]=[C:5]([CH:24]=[C:25]([C:27]([F:30])([F:29])[F:28])[CH:26]=1)[CH2:6][O:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH:14]=[CH:15][C:16]([CH3:23])=[CH:17][C:18]([O:20]CC)=[O:19].[OH-].[K+]>C(O)C>[F:1][C:2]([F:31])([F:32])[C:3]1[CH:4]=[C:5]([CH:24]=[C:25]([C:27]([F:29])([F:28])[F:30])[CH:26]=1)[CH2:6][O:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13]/[CH:14]=[CH:15]/[C:16](/[CH3:23])=[CH:17]/[C:18]([OH:20])=[O:19]

Participants

4

Reactant 2

HCID 14797Potassium HydroxideHCID 54229799HCID 54229799, compound

Product 1

HCID 131717627HCID 131717627, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

The above ester (10.2 mmol) was hydrolysed by potassium hydroxide (41.2 mmol) in aqueous ethanol at room temperature over 24 hours. After standard work-up, the residue was triturated with hexane to give (2E,4E) 11-(3',5'-bistrifluoromethylbenzyloxy)-3-methylundeca-2, 4-dienoic acid.

Workup

  1. customAfter standard work-up, the residue was triturated with hexane

Sources & evidence

ORD record
ord-f1e92ebba03a4d069173f1317924f78c
Source dataset
uspto-grants-1992_11
Patent number
US05162367

Reaction notes

Loading…