HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thiophenol → 1-(2'-Cyanobiphenyl-4-yl)methyl-6-phenylthio-3-propylpyrimidine-2,4(1H,3H)-dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thiophenol | HCID 7969 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 6-chloro-1-(2'-cyanobiphenyl-4-yl)methyl-3-propylpyrimidine-2,4(1H,3H)-dione | HCID 19811537 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | 1-(2'-Cyanobiphenyl-4-yl)methyl-6-phenylthio-3-propylpyrimidine-2,4(1H,3H)-dione | HCID 19811535 | — |
Reaction Steps
A mixture of 6-chloro-1-(2'-cyanobiphenyl-4-yl)methyl-3-propylpyrimidine-2,4(1H,3H)-dione (1 g), thiophenol (0.33 ml) and potassium carbonate (0.44 g) in acetonitrile (20 ml) was heated under reflux for 5 hours. The reaction mixture was allowed to cool and the precipitate was removed by filtration.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05162326 |
| Source dataset | uspto-grants-1992_11 |
| ORD ID | ord-8f9ff11134ee4baebdf686f1e2fa0016 |
| Source note | uspto-grants-1992_11 |