1,1-Diethyl-2-propylhydrazine → HCID 178463992, compound

HRID 373310Notes

Reaction equation

HRID 373310 reaction equation
Cl[C:2]1[C:7]([C:8]#[N:9])=[CH:6][C:5]([C:10]2[CH:15]=[CH:14][N+:13]([O-:16])=[CH:12][CH:11]=2)=[CH:4][N:3]=1.[CH2:17]([N:19](NCCC)[CH2:20][CH3:21])[CH3:18]>C(O)C>[C:8]([C:7]1[C:2]([NH:3][CH2:2][CH2:7][CH2:6][N:19]([CH2:17][CH3:18])[CH2:20][CH3:21])=[N:3][CH:4]=[C:5]([C:10]2[CH:15]=[CH:14][N+:13]([O-:16])=[CH:12][CH:11]=2)[CH:6]=1)#[N:9]

Participants

4

Reactant 2

HCID 1054241,1-Diethyl-2-propylhydrazineHCID 10243008HCID 10243008, compound

Product 1

HCID 178463992HCID 178463992, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

A mixture of 1 g 2-chloro-3-cyano-5,4'-bipyridine-1'-oxide and 1.35 g diethylamino-1-propylamine in 50 ml ethanol is refluxed for 4 hours. Subsequently, the mixture is concentrated under vacuum and the oil remaining behind is crystallized first from ethanol/diethyl ether and subsequently from methanol. Yield: 1.3 g (90.9% of the theoretical yield), with a melting point of 132° C.-133° C.

Workup

  1. temperatureis refluxed for 4 hours
  2. concentrationSubsequently, the mixture is concentrated under vacuum
  3. customthe oil remaining behind is crystallized first from ethanol/diethyl ether and subsequently from methanol
  4. customYield: 1.3 g (90.9% of the theoretical yield), with a melting point of 132° C.-133° C.

Sources & evidence

ORD record
ord-772540fb9f0c4d0dbcac9b19a8b6e5f0
Source dataset
uspto-grants-1992_11
Patent number
US05162533

Reaction notes

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