Methyl iodide → HCID 54061167, compound

Participants

Reaction Steps

To a solution of 4 g (0.03 mole) of aminoacetaldehyde diethylacetal in 60 l of tetrahydrofuran was added 3.3 g (0.033 mole) of triethylamine and 2.5 g (0.033 mole) of carbon disulfide. After the reaction mixture was stirred for one hour at 0° to 5° C., 4.7 g (0.033 mole) of methyl iodide was slowly added and stirred at 15°±5° C. for one hour. The solvent was removed from the reactant under reduced pressure, and water was added. The resulting mixture was extracted with ethyl acetate, dried over anhydrous sodium sulfate, and filtered. The solvent was removed under reduced pressure to obtain 6.54 g (yield 98%) of the desired liquid compound.

Provenance & Evidence