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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 373509Generated: October 26, 2026

Aminoethyl Nitrate → (2S, 4S)-N-(2-Nitroxyethyl)-6-fluoro-2',5'-dioxospiro[chroman-4,4'-imidazolidine]-2-carboxamide

https://huagongshe.com/reaction/373509

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAminoethyl NitrateHCID 26001—
Reactant(2S,4S)-6-fluoro-2',5'-dioxospiro[chroman-4,4'-imidazolidine]-2-carbonyl chlorideHCID 57210646—
Product(2S, 4S)-N-(2-Nitroxyethyl)-6-fluoro-2',5'-dioxospiro[chroman-4,4'-imidazolidine]-2-carboxamideHCID 6794438682.3%

Reaction Steps

The procedure similar to that as described in Example 8 was carried out with use of 2-nitroxyethylamine and (2S,4S)-6-fluoro-2',5'-dioxospiro[chroman-4,4'-imidazolidine]-2-carbonyl chloride (Reference Example 1) to give the desired compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05164391
Source datasetuspto-grants-1992_11
ORD IDord-7f29ef2f5ca4452490e5e7a87a023dc7
Source noteuspto-grants-1992_11