HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phthalic Anhydride → 2-[(8-chlorodibenz[b,f][1,4]oxazepin-10(11H)-yl)carbonyl]benzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phthalic Anhydride | HCID 6811 | — |
| Reactant | 8-Chloro-dibenz[b,f]-[1,4]oxazepine | HCID 838267 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 2-[(8-chlorodibenz[b,f][1,4]oxazepin-10(11H)-yl)carbonyl]benzoic acid | HCID 15780657 | 70.3% |
Reaction Steps
A stirred mixture of 8-chloro-dibenz[b,f]-[1,4]oxazepine (3.35 g) and phthalic anhydride (2.13 g) in THF (40 mL) was heated to reflux for 4 days. The mixture was concentrated and the residue was triturated with ether. The precipitated solid was filtered to give the title compound as a white solid (3.84 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05420270 |
| Source dataset | uspto-grants-1995_05 |
| ORD ID | ord-8e88240b57da42d69ecdb18994186b06 |
| Source note | uspto-grants-1995_05 |