5-(4'-(Bromomethyl)(1,1'-biphenyl)-2-yl)-1-trityl-1H-tetraazole → 2-butyl-1-[(2'-{N-triphenylmethyltetrazol-5-yl}{1,1'-biphenyl}-4-yl)methyl]-1H-thieno-[3,4-d]imidazole

Participants

Reaction Steps

This Step A compound can be prepared in a similar fashion to the preparation of 4'-[(2-butyl-1H-thieno[3,4-d]imidazol-1-yl)methyl][1,1'-biphenyl]-2-carboxylic acid t-butyl ester (Example 1, Step B) except that the alkylating agent used can be 2'-(N-triphenylmethyltetrazol-5-yl)biphen-4-yl methyl bromide in place of t-butyl-4'-bromomethylbiphenyl-2-carboxylate.

Provenance & Evidence