HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → (R)-2-Benzyl-succinic acid 1-benzyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | HCID 14213078 | HCID 14213078 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | (R)-2-Benzyl-succinic acid 1-benzyl ester | HCID 14213081 | 100.1% |
Reaction Steps
The resultant compound from Example 98 (11.76 g, 33.2 mmol) in methylene chloride (25 ml) was treated with trifluoroacetic acid (25 ml). After stirring at room temperature for 90 min the solvent was evaporated to afford 9.91 g (100%) of the desired product as a solid, m.p. 48°-51° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05164388 |
| Source dataset | uspto-grants-1992_11 |
| ORD ID | ord-4a6a9b24fb1e4fc49fc52630e2108c82 |
| Source note | uspto-grants-1992_11 |