HuagongsheHuagongshe Chemistry Print Report · For research reference only
Nitric Acid → 1-Carboxymethyl-7-nitroquinoxaline-2,3(1H,4H)-dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Nitric Acid | HCID 944 | — |
| Reactant | 2-(2,3-Dioxo-1,2,3,4-tetrahydroquinoxalin-1-yl)acetic acid | HCID 12938664 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Solvent | Acetic Anhydride | HCID 7918 | — |
| Product | 1-Carboxymethyl-7-nitroquinoxaline-2,3(1H,4H)-dione | HCID 19808446 | — |
Reaction Steps
Alternatively 1-carboxymethylquinoxaline-2,3(1H, 4H)-dione (Indian J. Chem. 20B, (1981), 822) could be nitrated using excess of 75% HNO3 in a mixture of acetic anhydride and acetic acid at 0° C. to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05166155 |
| Source dataset | uspto-grants-1992_11 |
| ORD ID | ord-fef4a347c47c4b3e9f65882eb08fdc6d |
| Source note | uspto-grants-1992_11 |