4-Bromobutyronitrile → 4-[4-(7-Methoxy-1-naphthyl)piperazino]butyronitrile

HRID 373806Notes

Reaction equation

[CH3:1][O:2][C:3]1[CH:12]=[C:11]2[C:6]([CH:7]=[CH:8][CH:9]=[C:10]2[N:13]2[CH2:18][CH2:17][NH:16][CH2:15][CH2:14]2)=[CH:5][CH:4]=1.Br[CH2:20][CH2:21][CH2:22][C:23]#[N:24]>>[CH3:1][O:2][C:3]1[CH:12]=[C:11]2[C:6]([CH:7]=[CH:8][CH:9]=[C:10]2[N:13]2[CH2:14][CH2:15][N:16]([CH2:20][CH2:21][CH2:22][C:23]#[N:24])[CH2:17][CH2:18]2)=[CH:5][CH:4]=1

Participants

Reactant 2

HCID 214124-Bromobutyronitrile

HCID 145667201-(7-Methoxynaphthalen-1-yl)piperazine

Product 1

HCID 198084814-[4-(7-Methoxy-1-naphthyl)piperazino]butyronitrile

Procedure

This compound was prepared according to the process described in Example 1, Stage C, from 4-(7-methoxy-1-naphthyl)piperazine and 4-bromobutyronitrile.

Workup

customThis compound was prepared

Sources & evidence

ORD record: ord-fc2a8015d53047f89733ef18ece63a09
Source dataset: uspto-grants-1992_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05166157

Reaction notes

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