4-Fluorobenzoyl chloride → HCID 19808470, compound

HRID 373817Notes

Reaction equation

HRID 373817 reaction equation
[CH3:1][O:2][C:3]1[CH:12]=[C:11]2[C:6]([CH:7]=[CH:8][CH:9]=[C:10]2[N:13]2[CH2:18][CH2:17][N:16]([CH2:19][CH2:20][CH2:21][CH2:22][NH2:23])[CH2:15][CH2:14]2)=[CH:5][CH:4]=1.[F:24][C:25]1[CH:33]=[CH:32][C:28]([C:29]([Cl:31])=[O:30])=[CH:27][CH:26]=1>>[ClH:31].[CH3:1][O:2][C:3]1[CH:12]=[C:11]2[C:6]([CH:7]=[CH:8][CH:9]=[C:10]2[N:13]2[CH2:18][CH2:17][N:16]([CH2:19][CH2:20][CH2:21][CH2:22][NH:23][C:29](=[O:30])[C:28]3[CH:32]=[CH:33][C:25]([F:24])=[CH:26][CH:27]=3)[CH2:15][CH2:14]2)=[CH:5][CH:4]=1

Participants

3

Reactant 2

HCID 678794-Fluorobenzoyl chlorideHCID 19808463HCID 19808463, compound

Product 1

HCID 19808470HCID 19808470, compoundYield 60%

Procedure

The expected compound was prepared from 1-(7-methoxy-1-naphthyl)-4-(4-amino-1-butyl)piperazine and 4-fluorobenzoyl chloride.

Sources & evidence

ORD record
ord-28efa4bf3a3d495eb4c4966cbd1d6673
Source dataset
uspto-grants-1992_11
Patent number
US05166156

Reaction notes

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