HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → Morpholin-2-ylmethanol hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Ethanol | HCID 702 | — |
| Reactant | (4-Benzylmorpholin-2-yl)methanol | HCID 2776358 | — |
| Reactant | 4-Benzyl-2-(methoxymethyl)morpholine | HCID 10353461 | — |
| Product | Morpholin-2-ylmethanol hydrochloride | HCID 19777263 | — |
Reaction Steps
N-Benzyl-2-hydroxymethylmorpholine prepared in the same manner as described in Synthetic Communication, Vol. 10 (1), pages 59-73, 1980 (1.3 g) is subjected to hydrogenolysis in hydrogen chloride-containing ethanol in the same manner as described in Reference Example 15 to give 2-hydroxymethylmorpholine hydrochloride (1.3 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05166203 |
| Source dataset | uspto-grants-1992_11 |
| ORD ID | ord-b5eda1b59790446a885aba860ea21104 |
| Source note | uspto-grants-1992_11 |