Acetic Acid → HCID 67905672, compound

Participants

Reaction Steps

0.5 g of p-[(R)-3-[[(RS)-2-hydroxy-3-phenoxypropyl]-amino]butyl]benzamide was warmed to 40° for 24 hours in 25 ml of acetic acid saturated with hydrochloric acid gas. Thereupon, the solvent was removed in vacuo and the crystalline residue was recrystallized from acetonitrile, and there was obtained p-[(R)-3-[[(RS)-2-acetoxy-3-phenoxypropyl]amino]butyl]-benzamide hydrochloride of m.p. 83°-85°, [α]D20 =-10° (c=0.6 in methanol), ε222 =15020, ε234 =13590.

Provenance & Evidence