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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 3740Generated: October 25, 2026

N-Acetyl-L-Cysteine → 2-Acetamido-3-[[2-[(4-sulfamoylphenyl)carbamoyl]phenyl]disulfanyl]propanoic acid

https://huagongshe.com/reaction/3740

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-Acetyl-L-CysteineHCID 12035—
Reactant4-(3-Oxo-1,2-benzothiazol-2-yl)benzenesulfonamideHCID 462938—
Product2-Acetamido-3-[[2-[(4-sulfamoylphenyl)carbamoyl]phenyl]disulfanyl]propanoic acidHCID 648355881.6%

Reaction Steps

This compound was prepared according to the method of Example 132 using 0.8 g (2.4 mmol) of 4-(3-oxo-3H-benzo[d]isothiazol-2-yl)benzenesulfonamide and 0.39 g (2.4 mmol) of N-acetyl-L-cysteine. The product was washed with ether and dried in vacuo to give 0.92 g of the title compound, mp 218°-220° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05734081
Source datasetuspto-grants-1998_03
ORD IDord-85957d48a087410d9c293b7d5c14f82e
Source noteuspto-grants-1998_03