N-(4-Methylphenyl)maleimide → HCID 19808813, compound

Participants

Reaction Steps

5 ml of xylene was added to a mixture of 580 mg of 2-(1-buten-2-yl)-5-methoxy-1-methoxymethylindole and 880 mg of N-(4-methylphenyl)maleimide. The mixture was refluxed for 1.5 hours. The solvent was removed by distillation under reduced pressure. The residue was purified by column chromatography (eluant: n-hexane/ethyl acetate=5/1 to 2/1) to obtain 510 mg (yield: 50%) of N-(4-methylphenyl)-1-ethyl-6-methoxy-9-methoxymethyl-1,2,3,4-tetrahydrocarbazole-3,4-dicarboximide as colorless crystals.

Provenance & Evidence