HCID 19808814, compound → HCID 19808762, compound

Participants

Reaction Steps

450 mg of N-phenyl-9-benzyl-7-bromo-1-bromomethyl-6-methoxycarbazole-3,4-dicarboximide was dissolved in 5 ml of methylene chloride. Thereto was added 0.5 ml of 20% dimethylamine-benzene solution. The resulting mixture was stirred for 1 hour at room temperature. To the reaction mixture was added 10 ml of methylene chloride. The resulting mixture was washed with an aqueous saturated sodium hydrogencarbonate solution and an aqueous saturated sodium chloride solution in this order, and dried over anhydrous magnesium sulfate. The solvent was removed by distillation under reduced pressure. The residue was recrystallized from n-propanol to obtain 370 mg (yield: 87%) of N-phenyl-9-benzyl-7-bromo-1-dimethylaminomethyl-6-methoxycarbazole-3,4-dicarboximide as yellow crystals.

Provenance & Evidence