HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Tiopronin → 2-[2-[[2-[(4-Sulfamoylphenyl)carbamoyl]phenyl]disulfanyl]propanoylamino]acetic acid
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Tiopronin | HCID 5483 | — |
| Edukt | 4-(3-Oxo-1,2-benzothiazol-2-yl)benzenesulfonamide | HCID 462938 | — |
| Produkt | 2-[2-[[2-[(4-Sulfamoylphenyl)carbamoyl]phenyl]disulfanyl]propanoylamino]acetic acid | HCID 6483559 | 92,3% |
Reaktionsschritte
This compound was prepared according to the method of Example 132 using 0.46 g (1.5 mmol) of 4-(3-oxo-3H-benzo[d]isothiazol-2-yl)benzenesulfonamide and 0.25 g (1.5 mmol) of 2-mercapto-propionylglycine. The product was washed with ether and dried in vacuo to give 0.65 g of the title compound, mp 254°-256° C.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US05734081 |
| Quelldatensatz | uspto-grants-1998_03 |
| ORD ID | ord-4e6baa83df414e8490e7a223e4d371a6 |
| Quellennotiz | uspto-grants-1998_03 |