HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethylformamide → cis-3-(Acetylthio)propenoyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethylformamide | HCID 6228 | — |
| Reactant | Oxalyl chloride | HCID 65578 | — |
| Reactant | cis-3-(Acetylthio)propenoic acid | HCID 86746379 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | cis-3-(Acetylthio)propenoyl chloride | HCID 86746380 | — |
Reaction Steps
To a mixture of 2.8 g (0.0162 mol) of cis-3-(acetylthio)propenoic acid and 0.1 ml of N,N-dimethylformamide in 50 ml of toluene under nitrogen was added 2.84 ml (0.0325 mol) of oxalyl chloride. After 3 h the solvents were removed to give cis-3-(acetylthio)propenoyl chloride. This crude product was used in the next step without any further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05166390 |
| Source dataset | uspto-grants-1992_11 |
| ORD ID | ord-d342777803884175a753a6f611084d0c |
| Source note | uspto-grants-1992_11 |