O-Butylhydroxylamine Hydrochloride → Methyl 2-[3-(1-n-butoxyiminoethyl)phenoxymethyl]phenylglyoxylate O-methyloxime

Participants

Reaction Steps

5.8 g (0.017 mol) of methyl 2-(3-acetylphenoxymethyl)phenylglyoxylate O-methyloxime and 2.5 g (0.020 mol) of n-butoxyamine hydrochloride in 60 ml of methanol are stirred at room temperature for 24 hours. The mixture is then hydrolyzed with water and extracted with methyl tert-butyl ether. The organic phase is washed with water, dried and concentrated. 5.0 g (71%) of the title compound are obtained as a colorless oil (compound no. 470).

Provenance & Evidence