HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → (alphaS)-alpha-Amino-3-thiophenepropanoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | l-aspartic acid, sodium salt | HCID 5460541 | — |
| Reactant | Hydroxy-3-(3-thienyl)acrylic acid | HCID 57047889 | — |
| Product | (alphaS)-alpha-Amino-3-thiophenepropanoic acid | HCID 819083 | 40% |
Reaction Steps
The procedure was largely as in Example 8. However, solution 1 contained only 20 g of hydroxy-3-(3-thienyl)acrylic acid and 19 g of L-aspartate. The product concentration was 11.5 g/l (58%) after the reaction. After ion-exchange chromatography, 7.9 g (40%) of L-3-(3-thienyl)alanine (2B) were obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05480786 |
| Source dataset | uspto-grants-1996_01 |
| ORD ID | ord-d33f108946e346f3b68f0b82226d6c52 |
| Source note | uspto-grants-1996_01 |