HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → 3-Bromopyridine-4-carbonyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 3-Bromoisonicotinic acid | HCID 817972 | — |
| Product | 3-Bromopyridine-4-carbonyl chloride | HCID 13597868 | — |
Reaction Steps
3-Bromopyridine-4-carboxylic acid (5.0 g) was dissolved in thionyl chloride (50 ml) and the solution heated under reflux for 4 hours, cooled and evaporated in vacuo. Re-evaporation of added toluene gave 3-bromopyridine4-carbonyl chloride, m.p.151°-154° C. (dec.) (5.45 g) as a green solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05480857 |
| Source dataset | uspto-grants-1996_01 |
| ORD ID | ord-f8192f4fac954ba7bd348f63b541c8bf |
| Source note | uspto-grants-1996_01 |