Phenethyl bromide → HCID 18997129, compound

Participants

Reaction Steps

A mixture of 10.9 g of 4-pyridinemethanol, 25 g of 2-bromoethylbenzene an 30 mL of dimethylformamide was stirred in a 90° oil bath for 3 hours. Removal of the solvent and crystallization of the residue from 30 mL of ethanol gave 23.4 g (80%) of 1-(2-phenylethyl)-4-hydroxymethylpyridinium bromide, mp 132°-134°. NMR (DMSO) δ8.9 (d, 2H): 8.0 (d, 2H); 7.2-7.4 (m, 5H); 6.0 (t, 1H), 4.8-4.9 (d+t, 4H); 3.3 (t, 2H).

Provenance & Evidence