HCID 54157997, compound → HCID 22861440, compound

HRID 374488Notes

Reaction equation

HRID 374488 reaction equation
[N+](C1C=CC(C([O:10][CH2:11][C@:12]2([CH3:26])[O:16][C:15](=[O:17])[N:14]([C:18]3[CH:23]=[CH:22][C:21]([O:24][CH3:25])=[CH:20][CH:19]=3)[CH2:13]2)=O)=CC=1)([O-])=O.[N+](C1C=CC(C(OC[C@H]2OC(=O)N(C3C=CC(OC)=CC=3)[C@H]2C)=O)=CC=1)([O-])=O>>[CH3:25][O:24][C:21]1[CH:20]=[CH:19][C:18]([N:14]2[CH2:13][C@@:12]([CH2:11][OH:10])([CH3:26])[O:16][C:15]2=[O:17])=[CH:23][CH:22]=1

Participants

3

Reactant 2

HCID 54157997HCID 54157997, compoundHCID 57080354HCID 57080354, compound

Product 1

HCID 22861440HCID 22861440, compoundYield 90%

Procedure

The same procedure of Reference Example 11 was repeated except that (R)-(-)-3-(4-methoxyphenyl)-5-methyl-2-oxooxazolidin-5-ylmethyl p-nitrobenzoate obtained in Reference Example 9 was used in lieu of (4S, 5S)-(-)-3-(4-methoxyphenyl)-4-methyl-2-oxooxazolidin-5-ylmethyl p-nitrobenzoate to give the title compound (yield 90% ).

Workup

  1. customobtained in Reference Example 9

Sources & evidence

ORD record
ord-a67a9febbf954a3885334e1d46017131
Source dataset
uspto-grants-1996_01
Patent number
US05480899

Reaction notes

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