HCID 15281825, compound → HCID 18997196, compound

HRID 374498Notes

Reaction equation

HRID 374498 reaction equation
[NH2:1][C:2]1[CH:7]=[CH:6][C:5]([N:8]2[CH2:12][CH:11]([CH2:13][O:14][C:15]3[CH:23]=[CH:22][C:18]([C:19]([OH:21])=[O:20])=[CH:17][CH:16]=3)[O:10][C:9]2=[O:24])=[CH:4][CH:3]=1.NC1C=CC(N2[CH2:36][CH:35](COC3C=CC(C(OC)=O)=CC=3)[O:34]C2=O)=CC=1>>[C:35]([NH:1][C:2]1[CH:7]=[CH:6][C:5]([N:8]2[CH2:12][CH:11]([CH2:13][O:14][C:15]3[CH:23]=[CH:22][C:18]([C:19]([OH:21])=[O:20])=[CH:17][CH:16]=3)[O:10][C:9]2=[O:24])=[CH:4][CH:3]=1)(=[O:34])[CH3:36]

Participants

3

Reactant 2

HCID 15281825HCID 15281825, compoundHCID 18997194HCID 18997194, compound2×

Product 1

HCID 18997196HCID 18997196, compoundYield 88%

Procedure

The same procedure of Example 10 was repeated except that 4-[3-(4-aminophenyl)-2-oxooxazolidin-5-yl]methoxy benzoic acid (compound 114) obtained Example 11 was used in lieu of methyl 4-[3-(4-aminophenyl)-2-oxooxazolidin-5-yl]methoxybenzoate to give the title compound (compound 115) in a yield of 88%.

Workup

  1. customobtained Example 11

Sources & evidence

ORD record
ord-b549fa47db4a4c62b373be34399c2a19
Source dataset
uspto-grants-1996_01
Patent number
US05480899

Reaction notes

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