HCID 18997191, compound → HCID 18997217, compound

HRID 374500Notes

Reaction equation

HRID 374500 reaction equation
[CH3:1][C:2]1[CH:7]=[CH:6][C:5]([S:8]([N:11]2[CH2:15][CH:14]([CH2:16][O:17][C:18]3[CH:33]=[CH:32][C:21]([C:22]([O:24]CC4C=CC=CC=4)=[O:23])=[CH:20][CH:19]=3)[O:13][C:12]2=[O:34])(=[O:10])=[O:9])=[CH:4][CH:3]=1.C(N1CC(COC2C=CC(C(OCC3C=CC=CC=3)=O)=CC=2)OC1=O)(=O)C1C=CC=CC=1>>[CH3:1][C:2]1[CH:7]=[CH:6][C:5]([S:8]([N:11]2[CH2:15][CH:14]([CH2:16][O:17][C:18]3[CH:19]=[CH:20][C:21]([C:22]([OH:24])=[O:23])=[CH:32][CH:33]=3)[O:13][C:12]2=[O:34])(=[O:9])=[O:10])=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 18997191HCID 18997191, compound2×HCID 18997201HCID 18997201, compound

Product 1

HCID 18997217HCID 18997217, compoundYield 62%

Procedure

The same procedure of Example 13 was repeated except that benzyl 4-[3-(4-methylbenzenesulfonyl)-2-oxooxazolidin-5-yl]methoxybenzoate (compound 123) obtained in Example 5 was used in lieu of benzyl 4-(3-benzoyl-2-oxooxazolidin-5-yl)methoxybenzoate to give the title compound (compound 135) in a yield of 62%.

Workup

  1. customobtained in Example 5

Sources & evidence

ORD record
ord-fe4efa78bfac4a05ab3ea11a83919893
Source dataset
uspto-grants-1996_01
Patent number
US05480899

Reaction notes

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