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HRID374501

反应详情

EQUATION

反应方程式

HRID 374501 的结构方程式

REACTANTS

反应物

2
结构：COc1ccc(N2C[C@](C)(COc3ccc(C#N)cc3)OC2=O)cc1
HCID54210872

未命名化合物

结构：COc1ccc(N2C(=O)O[C@H](COc3ccc(C#N)cc3)[C@@H]2C)cc1
HCID67732715

未命名化合物

PRODUCTS

生成物

1
结构：COc1ccc(N2C[C@](C)(COc3ccc(C=O)cc3)OC2=O)cc1
HCID53999981

未命名化合物

收率 85%

PROCEDURE

实验过程

The same procedure of Example 16 was repeated except that 4-[(R)-(-)-3-(4-methoxyphenyl)-5-methyl-2-oxooxazolidin-5-yl]methoxybenzonitrile obtained in Reference Example 15 was used in lieu of 4-[(4S, 5S)-(-)-3-(4-methoxyphenyl)-4-methyl-2-oxooxazolidin-5-yl]methoxybenzonitrile to give the title compound (compound 44) as an oil (yield 85%).

WORKUP

后处理

  1. customobtained in Reference Example 15