Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 374505Generated: November 1, 2026

Methylparaben → HCID 18997214, compound

https://huagongshe.com/reaction/374505

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethylparabenHCID 7456—
ReactantPotassium CarbonateHCID 11430—
ReactantHCID 18997188HCID 18997188—
SolventDimethylformamideHCID 6228—
ProductHCID 18997214HCID 1899721490.1%

Reaction Conditions

Temperature60 °C

Reaction Steps

In 20 ml of N,N-dimethylformamide was dissolved 1.50 g of 3-(4-chlorophenyl)-2-oxooxazolidin-4-ylmethyl methanesulfonate and 0.80 g of methyl 4-hydroxybenzoate. To the solution was added 0.80 g of anhydrous potassium carbonate, and the mixture was stirred at 60° C. for 12 hours. The reaction mixture was concentrated under reduced pressure and water was added thereto. The obtained residue was recrystallized from methanol to give 1.60 g of the title compound (compound 176) in a yield of 90%.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05480899
Source datasetuspto-grants-1996_01
ORD IDord-bde36151ade341c8a9f1d09432844f7a
Source noteuspto-grants-1996_01