Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Methylparaben | HCID 7456 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | HCID 18997188 | HCID 18997188 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 18997214 | HCID 18997214 | 90.1% |
Reaction Steps
In 20 ml of N,N-dimethylformamide was dissolved 1.50 g of 3-(4-chlorophenyl)-2-oxooxazolidin-4-ylmethyl methanesulfonate and 0.80 g of methyl 4-hydroxybenzoate. To the solution was added 0.80 g of anhydrous potassium carbonate, and the mixture was stirred at 60° C. for 12 hours. The reaction mixture was concentrated under reduced pressure and water was added thereto. The obtained residue was recrystallized from methanol to give 1.60 g of the title compound (compound 176) in a yield of 90%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US05480899 |
|---|
| Source dataset | uspto-grants-1996_01 |
|---|
| ORD ID | ord-bde36151ade341c8a9f1d09432844f7a |
|---|
| Source note | uspto-grants-1996_01 |
|---|