HCID 18997188, compound → HCID 18997199, compound

HRID 374506Notes

Reaction equation

HRID 374506 reaction equation
CS([O:5][CH2:6][CH:7]1[CH2:11][O:10][C:9](=[O:12])[N:8]1[C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1)(=O)=O.CS(OCC1COC(=O)N1[C:31]1[CH:36]=[CH:35][C:34](Cl)=[CH:33][CH:32]=1)(=O)=O>>[C:13]1([N:8]2[CH:7]([CH2:6][O:5][C:31]3[CH:32]=[CH:33][C:34]([C:9]([O:10][CH3:11])=[O:12])=[CH:35][CH:36]=3)[CH2:11][O:10][C:9]2=[O:12])[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1

Participants

3

Reactant 2

HCID 18997188HCID 18997188, compoundHCID 19420811HCID 19420811, compound

Product 1

HCID 18997199HCID 18997199, compoundYield 60%

Procedure

The same procedure of Example 22 was repeated except that 3-phenyl-2-oxooxazolidin-4-ylmethyl methanesulfonate obtained in Reference Example 20 was used in lieu of 3-(4-chlorophenyl)-2-oxooxazolidin-4-ylmethyl methanesulfonate to give the title compound (compound 177) in a yield of 60%.

Workup

  1. customobtained in Reference Example 20

Sources & evidence

ORD record
ord-a4d2d0326a8b48e3a5462654d154808a
Source dataset
uspto-grants-1996_01
Patent number
US05480899

Reaction notes

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