HCID 18997199, compound → HCID 18997210, compound

HRID 374508Notes

Reaction equation

HRID 374508 reaction equation
[C:1]1([N:7]2[CH:11]([CH2:12][O:13][C:14]3[CH:23]=[CH:22][C:17]([C:18]([O:20]C)=[O:19])=[CH:16][CH:15]=3)[CH2:10][O:9][C:8]2=[O:24])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.ClC1C=CC(N2C(COC3C=CC(C(OC)=O)=CC=3)COC2=O)=CC=1>>[C:1]1([N:7]2[CH:11]([CH2:12][O:13][C:14]3[CH:15]=[CH:16][C:17]([C:18]([OH:20])=[O:19])=[CH:22][CH:23]=3)[CH2:10][O:9][C:8]2=[O:24])[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

Participants

3

Reactant 2

HCID 18997199HCID 18997199, compound2×HCID 18997214HCID 18997214, compound

Product 1

HCID 18997210HCID 18997210, compoundYield 61%

Procedure

The same procedure of Example 25 was repeated except that methyl 4-(3-phenyl-2-oxooxazolidin-4-yl)methoxybenzoate (compound 177) obtained in Example 23 was used in lieu of methyl 4-[3-(4-chlorophenyl)-2-oxooxazolidin-4-yl]methoxybenzoate to give the title compound (compound 180) in a yield of 61%.

Workup

  1. customobtained in Example 23

Sources & evidence

ORD record
ord-569d02ac39364451bc5e404132828358
Source dataset
uspto-grants-1996_01
Patent number
US05480899

Reaction notes

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