Methanol → HCID 54504049, compound

Participants

Reaction Steps

In 20 ml of methanol was dissolved 200 mg of 4-(3-phenyl-2-oxooxazolidin-5-yl)methoxycinnamic acid (compound 181) obtained in Example 27. Concentrated sulfic acid (0.05 ml) was added to the solution, and the mixture was refluxed with heating for 16 hours. The reaction mixture was concentrated under reduced pressure and the obtained residue was washed with water and methanol to give 195 mg of the title compound (compound 185) in a yield of 94%.

Provenance & Evidence