HCID 54504049, compound → HCID 18997213, compound

Participants

Reaction Steps

A 200 mg quantity of 10% palladium carbon was added to a tetrahydrofuran (50 ml) solution of 1.75 g of methyl 4-(3-phenyl-2-oxooxazolidin-5-yl)methoxycinnamate (compound 185) obtained in Example 29. The mixture was stirred at room temperature for 2.5 hours in a stream of hydrogen at 3 atmospheric pressure. The reaction mixture was filtered, and the filtrate was concentrated under reduced pressure and washed with methanol to give 1.59 g of the title compound (compound 189) in a yield of 88%.

Provenance & Evidence