HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → (S)-(-)-2-Nitro-1-(2-oxiranylmethyl)-1H-imidazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | (S)-(+)-alpha-(chloromethyl)-2-nitro-1H-imidazole-1-ethanol | HCID 11052772 | — |
| Product | (S)-(-)-2-Nitro-1-(2-oxiranylmethyl)-1H-imidazole | HCID 11768967 | 65.1% |
Reaction Steps
Alternatively, reaction of 0.56 g of (S)-(+)-α-(chloromethyl)-2-nitro-1H-imidazole-1-ethanol with 3 mL of 10% aqueous sodium hydroxide at 25° C. for 30 minutes followed by further processing as above gives 0.3 g of the product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05481000 |
| Source dataset | uspto-grants-1996_01 |
| ORD ID | ord-481800be55f8470ea8a30e5ede74e192 |
| Source note | uspto-grants-1996_01 |