Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Dodecylamine | HCID 13583 | — |
| Reactant | Ethyl orthoformate | HCID 31214 | — |
| Reactant | 3-methylisoxazol-5(4H)-one | HCID 535031 | — |
| Product | HCID 178443241 | HCID 178443241 | 29% |
Reaction Steps
3 g of triethyl orthoformate are added to 3.7 g of n-dodecylamine and 2 g of 3-methylisoxazol-5(4H)-one and the reaction mixture is heated at 60° C. for 20 hours. Thereupon, it is filtered over silica gel in hexane/ether/CH2Cl2 =1:1:3 and the desired product obtained is recrystallized in hexane. Yield 29%, m.p. 57° C., UV (EtOH): 311 nm (ε=18530).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US05481001 |
|---|
| Source dataset | uspto-grants-1996_01 |
|---|
| ORD ID | ord-ff2a4dd1e6fd4eeeb8c5a3ce51a6f905 |
|---|
| Source note | uspto-grants-1996_01 |
|---|
