L-Alanine → HCID 22564093, compound

HRID 374605Notes

Reaction equation

HRID 374605 reaction equation
[C:1](#[N:4])[CH2:2]O.[NH2:5][C@H:6]([C:8]([OH:10])=[O:9])[CH3:7]>>[C:1]([CH2:2][NH:5][CH:6]([CH3:7])[C:8]([OH:10])=[O:9])#[N:4]

Participants

3

Reactant 2

HCID 5950L-Alanine2×HCID 7857Hydroxyacetonitrile

Product 1

HCID 22564093HCID 22564093, compound

Procedure

One suitable reaction scheme for the synthesis of an intermediate starting with alanine is shown in Scheme I. In step(a) alanine is contacted with glycolonitrile to form 2-(cyanomethylamino)propionic acid (I). The molar ratio of alanine to glycolonitrile is generally about 1:1 with a slight excess of glycolonitrile preferred. ##STR2##

Workup

  1. customOne suitable reaction scheme
  2. customfor the synthesis of an intermediate

Sources & evidence

ORD record
ord-0d44c945a4cb4214b3c292e3a05352d2
Source dataset
uspto-grants-1996_01
Patent number
US05481018

Reaction notes

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