HCID 18996954, compound → HCID 18996983, compound

Participants

Reaction Steps

A suspension of methyl 4,5-dimethoxy-6-fluoro-9,10-dihydro-9,10-dioxoanthracene 2-carboxylate (306 mg) in 47% aqueous hydrobromic acid was stirred at reflux for 18 hours. The yellow suspension was cooled and concentrated to yield a yellow solid. This was triturated with water, filtered, washed well with water and dried to yield 9,10-dihydro-4,5-dihydroxy-9,10-dioxo-6-fluoro-anthracene 2-carboxylic acid as a deep yellow solid, m.p. >275° C.

Provenance & Evidence