tert-Butyl acrylate → HCID 136203549, compound

HRID 374772Notes

Reaction equation

HRID 374772 reaction equation
Br[C:2]1[CH:3]=[CH:4][C:5]([O:20][CH2:21][CH2:22][CH3:23])=[C:6]([C:8]2[NH:17][C:16](=[O:18])[C:15]3[C:10](=[C:11]([CH3:19])[CH:12]=[CH:13][CH:14]=3)[N:9]=2)[CH:7]=1.[C:24]([O:28][C:29]([CH3:32])([CH3:31])[CH3:30])(=[O:27])[CH:25]=[CH2:26]>>[CH3:19][C:11]1[CH:12]=[CH:13][CH:14]=[C:15]2[C:10]=1[N:9]=[C:8]([C:6]1[CH:7]=[C:2]([CH:3]=[CH:4][C:5]=1[O:20][CH2:21][CH2:22][CH3:23])[CH:26]=[CH:25][C:24]([O:28][C:29]([CH3:32])([CH3:31])[CH3:30])=[O:27])[NH:17][C:16]2=[O:18]

Participants

3

Reactant 2

HCID 15458tert-Butyl acrylateHCID 136110484HCID 136110484, compound

Product 1

HCID 136203549HCID 136203549, compound

Procedure

The title compound was prepared from 2-(5-bromo-2-n-propoxyphenyl)-8 -methylquinazolin-4(3H)-one (Preparation 11) and t-butyl acrylate following the procedure of Example 9 and was obtained as colorless crystals (18%), m.p. 196°-197° C. Found: C,71.54; H,6.90; N,6.69. C25H28N2O4 requires C,71.41; H,6.71; N,6.66%.

Sources & evidence

ORD record
ord-d0ace213ee654c439ce07c30a46841af
Source dataset
uspto-grants-1996_01
Patent number
US05482941

Reaction notes

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