反应详情

3-Carbamoyl-2-nitrobenzamide (0.6 g, 0.0029 mol) was dissolved in ethanol (50 ml) and the solution stirred with 5% palladium on charcoal catalyst (0.1 g) under a hydrogen atmosphere at 50 p.s.i. (3.45 bar) and 50° C. for 5 hours. The catalyst was removed by filtration, the solvent evaporated under vacuum and the residue crystallized from water to give the title compound as a grey solid (0.26 g, 50%), m.p.284°-288° C. Found: C,53.49; H,5.00; N,23.31. C8H9N3O2 requires C,53.62; H,5.06; N,23.45%.

1. customThe catalyst was removed by filtration
2. customthe solvent evaporated under vacuum
3. customthe residue crystallized from water