HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydroxyphenylacetic acid → HCID 23369910, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydroxyphenylacetic acid | HCID 127 | — |
| Reactant | Benzene | HCID 241 | — |
| Reactant | p-Toluenesulfonic acid | HCID 6101 | — |
| Reactant | Cyclohexanol | HCID 7966 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 23369910 | HCID 23369910 | 104.6% |
Reaction Steps
Cyclohexyl alcohol (6 g), 4-hydroxyphenylacetic acid (7.6 g), p-toluenesulfonic acid (1 g) and benzene (300 mL) were refluxed with continuous water separation for 8 hours. The mixture was cooled and washed with a 10% Na2CO3 solution, then with water. Drying over MgSO4 and evaporation of the solvent in vacuo gave 12.24 g of cyclohexyl 4-hydroxyphenylacetate. That compound can be represented by the formula: ##STR25##
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05482961 |
| Source dataset | uspto-grants-1996_01 |
| ORD ID | ord-80487366445e49ecb2f1bbcdefafbb81 |
| Source note | uspto-grants-1996_01 |