反应详情

51 g of 2-(1-chloro-2,2,2-trifluoroethyl)-2-trifluoromethyl-1,3-benzodioxole from Example 2 or 17 were dissolved in 300 ml of carbon tetrachloride, and 0.5 g of anhydrous FeCl3 was added. 32 g of bromine were then added and the mixture was stirred under reflux for 3 hours. After cooling, the mixture was washed with 10% strength NaHSO3 solution, dried with MgSO4 and distilled. The yield was 49 g (63% of theory), and the boiling point was 94°-98° C. under 8 mbar.

1. temperatureunder reflux for 3 hours
2. temperatureAfter cooling
3. washthe mixture was washed with 10% strength NaHSO3 solution
4. dry with materialdried with MgSO4
5. distillationdistilled