Acetic Acid → HCID 18996349, compound

Participants

Reaction Steps

One equivalent of the above aldehyde, one equivalent of 2-amino-1-(3-chlorophenyl)ethanol, one equivalent of acetic acid, and 1.5 equivalents of sodium triacetoxyborohydride in 1,2-dichloroethane is stirred at room temperature for 1 hour. The solvent is evaporated in vacuo. The residue dissolved in 2.5N sodium hydroxide in ethyl alcohol, heated at reflux temperature for one hour, and evaporated in vacuo. The residue is passed through an ion exchange column to give the title compound.

Provenance & Evidence