Formaldehyde → HCID 21463222, compound

HRID 374991Notes

Reaction equation

Cl.[CH3:2][C:3]1[CH:4]=[C:5]([CH:31]=[C:32]([CH3:34])[CH:33]=1)[CH2:6][NH:7][CH:8]1[C:17]2[N:12]([C:13](=[O:30])[C:14]3[CH:27]=[C:26]([CH3:28])[C:25]([CH3:29])=[CH:24][C:15]=3[C:16]=2[C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=2)[CH2:11][CH2:10][CH2:9]1.[CH2:35]=O.[BH4-].[Na+]>>[CH3:28][C:26]1[C:25]([CH3:29])=[CH:24][C:15]2[C:16]([C:18]3[CH:19]=[CH:20][CH:21]=[CH:22][CH:23]=3)=[C:17]3[N:12]([C:13](=[O:30])[C:14]=2[CH:27]=1)[CH2:11][CH2:10][CH2:9][CH:8]3[N:7]([CH2:6][C:5]1[CH:4]=[C:3]([CH3:2])[CH:33]=[C:32]([CH3:34])[CH:31]=1)[CH3:35]

Participants

Reactant 3

HCID 712Formaldehyde

HCID 4311764Sodium borohydride

HCID 21463326HCID 21463326, compound

Product 1

HCID 21463222HCID 21463222, compound

Procedure

The compound obtained in Example 233 and formalin were reacted and treated with sodium borohydride in the same manner as in Example 233 to yield the title compound as colorless crystals.

Sources & evidence

ORD record: ord-1ba8dbefc59c4f2ca94e83e6a8705194
Source dataset: uspto-grants-1996_01
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05482967

Reaction notes

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