反应详情

Phenylglyoxal monohydrate (304 mg, 2 mM) and sec-butylbenzene (0.62 ml, 4 mM) were dissolved in dichloroethane (4 ml), titanium tetrachloride (0.33 ml, 3 mM) was added, and reacted at room temperature for 2.5 hours. Using the same procedure as in Example 1, 4'-sec-butylbenzoin was obtained as crystal (200.6 mg, 37.3% yield).

1. customreacted at room temperature for 2.5 hours