Tert-Butylbenzene → HCID 23513088, compound

HRID 375043Notes

Reaction equation

HRID 375043 reaction equation
O.[C:2]1([C:8]([CH:10]=[O:11])=[O:9])[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[C:12]([C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1)([CH3:15])([CH3:14])[CH3:13]>ClC(Cl)C.[Ti](Cl)(Cl)(Cl)Cl>[C:12]([C:16]1[CH:21]=[CH:20][C:19]([CH:10]([OH:11])[C:8](=[O:9])[C:2]2[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=2)=[CH:18][CH:17]=1)([CH3:15])([CH3:14])[CH3:13]

Participants

5

Reactant 2

HCID 7366Tert-ButylbenzeneHCID 12215922Glyoxal, phenyl-, hydrate

Product 1

HCID 23513088HCID 23513088, compound

Reagents, catalysts & solvents 2

HCID 24193Titanium TetrachlorideCatalystHCID 63651,1-DichloroethaneSolvent

Procedure

Phenylglyoxal monohydrate (304 mg, 2 mM) and tert-butylbenzene (0.62 ml, 4 mM) were dissolved in dichloroethane (2 ml), titanium tetrachloride (0.33 ml, 3 mM) was added, and reacted at room temperature for 2.5 hours. Using the same procedure as in Example 1, 4'-tert-butylbenzoin was obtained as crystal (216.9 mg, 40.5% yield).

Workup

  1. customreacted at room temperature for 2.5 hours

Sources & evidence

ORD record
ord-1c3f52eeb9994190ba31ea529084ea7b
Source dataset
uspto-grants-1996_01
Patent number
US05484689

Reaction notes

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