HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,2,3,4-Tetramethylbenzene → 2',3',4',5'-Tetramethylbenzoin
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,2,3,4-Tetramethylbenzene | HCID 10263 | — |
| Reactant | Glyoxal, phenyl-, hydrate | HCID 12215922 | — |
| Catalyst | Titanium Tetrachloride | HCID 24193 | — |
| Solvent | 1,1-Dichloroethane | HCID 6365 | — |
| Product | 2',3',4',5'-Tetramethylbenzoin | HCID 18994075 | 70.7% |
Reaction Steps
Phenylglyoxal monohydrate (304 mg, 2 mM) and 1,2,3,4-tetramethylbenzene (0.60 ml, 4 mM were dissolved in dichloroethane (5 ml), titanium tetrachloride (0.33 ml, 3 mM) was added, and reacted at room temperature for 10 minutes. Using the same procedure as in Example 1, 2',3',4',5'-tetramethylbenzoin was obtained (378.2 mg, 70.7% yield).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05484689 |
| Source dataset | uspto-grants-1996_01 |
| ORD ID | ord-0e506425ac1548dcbb49ef5fc9ff1ca7 |
| Source note | uspto-grants-1996_01 |