HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Anhydride → N-(hydroxymethyl)acetamide acetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Anhydride | HCID 7918 | — |
| Reactant | Formicin | HCID 69365 | — |
| Catalyst | Pyridine | HCID 1049 | — |
| Product | N-(hydroxymethyl)acetamide acetate | HCID 86745977 | 900% |
Reaction Steps
Acetic anhydride (25 g) and pyridine (10 drops) is added to N-(hydroxymethyl)acetamide (9 g, 0.1 mol). The reaction mixture is stirred overnight at room temperature, concentrated in vacuo and chased with xylene to give the title product as an oil (11.9 g, 0.9 mol) which is identified by 1HNMR spectral analysis.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05484807 |
| Source dataset | uspto-grants-1996_01 |
| ORD ID | ord-452be2e369b949f39458cfbb65e5b732 |
| Source note | uspto-grants-1996_01 |