2-Propenoic acid, 3-(methoxyphenyl)- → 1H-Purine-2,6-dione, 3,7-dihydro-1,3-diethyl-8-(2-(2-methoxyphenyl)ethenyl)-, (E)-

Participants

Reaction Steps

Substantially the same procedure as in Example 7 was repeated using 2.5 g (12.6 mmol) of 5,6-diamino-1,3-diethyluracil and 2.48 g (13.9 mmol) of 2-methoxycinnamic acid. Then, the resultant crude crystals were recrystallized from tetrahydrofuran/water to give 990 mg (yield 24%) of Compound 108 as yellow grains.

Provenance & Evidence